Innovative COVID treatment puts a cork on virus’s entry point to cell – The Jerusalem Post

An innovative treatment for COVID-19 uses a molecular “super cork” to jam the entry point used by the SARS-CoV-2 virus to enter the cell, bypassing issues that could arise with other treatments which target a spike protein on the virus, Weizmann Institute of Science announced on Wednesday.
The treatment, described in a study published in Nature Microbiology, was developed by Weizmann researchers in collaboration with the Pasteur Institute in France and the National Institutes of Health (NIH) in the US.

Most treatments and vaccines for SARS-CoV-2 target the spike protein on the virus’s outer envelope, but this protein could mutate in future variants, negatively effecting the efficacy of such treatments. The Weizmann researchers decided to take a different approach, targeting the angiotensin-converting enzyme 2 (ACE2) receptors through which the virus enters the cell. This approach is not susceptible to new variants.

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